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Written by Will Boggs, MD
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Thursday, 24 July 2008 |
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Long-term strontium ranelate treatment reduces the risk of nonvertebral and vertebral fractures in women with postmenopausal osteoporosis, according to a report in the June issue of Arthritis & Rheumatism. |
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Written by Ramaz Mitaishvili
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Thursday, 24 July 2008 |
More than 70% of obese patients do not receive adequate doses of vancomycin, possibly resulting in subtherapeutic concentrations, according to Dallas-based researchers. Criteria that are more stringent suggest that this may also be true of a much wider group of patients.
In the June issue of the American Journal of Medicine, Dr. Ronald G. Hall II of Texas Tech University and colleagues note that although body weight is the preferred method of calculating vancomycin dosage, many studies continue to use a flat dosing regimen of 1 g every 12 hours to evaluate new agents for the treatment of gram-positive infections, including methicillin-resistant Staphylococcus aureus. |
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Written by Lewis Krauskopf
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Thursday, 24 July 2008 |
Health insurer WellPoint Inc said on Wednesday profit fell 10 percent, as medical costs ate further into premiums, but its shares rose more than 6 percent as results beat projections, helped by strength in its pharmacy and behavioral health businesses.
Although the largest U.S. health insurer by membership tempered its full-year profit and enrollment forecasts, it appeared to avoid any major negative surprises in its report, amid a brutal year for health insurer stocks. |
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Written by Ramaz Mitaishvili
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Thursday, 24 July 2008 |
Among patients with pulmonary arterial hypertension (PAH), those with germline mutations in the gene encoding bone morphogenetic protein receptor 2 (BMPR2) present at an earlier age and with more severe hemodynamic compromise, according to findings from a French study.
Dr. Marc Humbert of Universite Paris-Sud 11 and colleagues screened 223 consecutive patients with PAH for point mutations and large size rearrangements of BMPR2. Clinical, functional and hemodynamic characteristics were compared between carriers and noncarriers. |
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